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Read about blood sugar, cholesterol, homemade cosmetics, find salicylate free strategies and more.



Cruelty Free  Supplements

Cruelty Free Cosmetics
 


Low Carbohydrate, Low Fat Cookbooks.

cover
Dr. Atkins' Vita-Nutrient Solution : Nature's Answer to Drugs


PDR for Nutritional Supplements



The PDR Family Guide to Nutritional Supplements : An Authoritative A-to-Z  

The Magazine - Pdr For Nutritional Supplements


A Practical A-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs, and Food Supplements



The Insulin-Resistance Diet : How to Turn Off Your Body's Fat-Making Machine



Blood Sugar Blues : Overcoming the Hidden Dangers of Insulin Resistance
by Miryam Ehrlich Williamson, R. Paul St. Amand M.D.


Insulin Resistance: A Medical Dictionary, Bibliography, And Annotated Research Guide To Internet References

Magnesium and the Insulin Resistance Syndrome (Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, 1088)



Insulin Resistance and Cardiovascular Disease


Syndrome X: The Complete Nutritional Program to Prevent and Reverse Insulin Resistance



The Insulin Factor: Can't Lose Weight? Can't Concentrate? Can't Resist Sugar? Could Syndrome X Be Your Problem



Balance Your Blood Sugar Naturally to Beat Disease, Lose Weight, Gain Energy, and Feel Great


The Low Blood Sugar Handbook: You Don't Have to Suffer....



The Low Blood Sugar Cookbook: Sugarless Cooking for Everyone



What Makes My Blood Glucose Go Up...And Down? And 101 Other Frequently Asked Questions About Your Blood Glucose Levels



LOW BLOOD SUGAR Hypoglycemia: The 20th Century Epidemic?



101 Tips For Improving Your Blood Sugar



Reactive Hypoglycemia - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References


Preventing Reactive Hypoglycemia: The Great Medical Dilemma


The New Glucose Revolution: The Authoritative Guide to the Glycemic Index--the Dietary Solution for Lifelong Health



Atkins Diabetes Revolution : The Groundbreaking Approach to Preventing and Controlling Type 2 Diabetes



The G.I. Handbook : How the Glycemic Index Works
 



Eradication of H. Pylori shown to improve hypoglycemia

H. Pylori may contribute to hypoglycemia

H. Pylori may lead to lower glucose concentrations in women and should be considered when interpreting concentrations bordering on diabetes

Both obesity and type II diabetes may be associated with an increased incidence of H. pylori-colonization

Diet, Exercise Dramatically Delay Type 2 Diabetes

CDC - Exercise can delay onset of diabetes

Exercise Reduces Diabetes by Reducing Insulin Resistance
 


The Healing Power of Exercise : Your Guide to Preventing and Treating Diabetes, Depression, Heart Disease, High Blood Pressure, Arthritis, and More


The Diabetic Athlete
 


Handbook of Exercise in Diabetes


The Fitness Book: For People With Diabetes

How blood sugar works

CDC's Diabetes Program - Publications & Products - Take Charge of Your Diabetes - Glossary


Diabetes breakthrough
Toronto scientists cure disease in mice

Type 2 Diabetes In the Genes

Caffiene interferes with insulin metabolism and affects both diabetes and hypoglycemia

Does Flavanol Intake Influence Mortality from Nitric Oxide-Dependent Processes? Ischemic heart disease, stroke, diabetes mellitus, and cancer in Panama

Tips on controlling sugar cravings

Sugar cravings subside with persistent and consistent EFT

The Analyst - Internet Health Report: Condition: Sugar Craving

 

Supplements for Blood Sugar Control

Following are a list of supplements that may be helpful in managing blood sugars for those with blood sugar disorders like hypoglycemia or diabetes.  You should check with your  health care provider for further advice.

You may also be interested in:

Diseases,  Medical Conditions and Deficiencies that are associated with Blood Sugar and Insulin Control

Biotin
*Sal-FreeTM


Biotin is a B vitamin that aids in the metabolism of carbohydrates, fats and proteins. A deficiency can cause high blood sugar as well as hair loss, depression, inflammation or palor of the skin and mucous membranes, insomnia, loss of appetite, muscular pain, nausea and soreness of the tongue.  Deficiency in adults is rare because biotin can be produced in the intestine with the help of beneficial bacteria. 

Biotin is needed for healthy hair and skin.  It promotes healthy sweat glands, nerve tissue and bone marrow.

A genetically inherited sensitivity to sugar was improved in rats who had a higher biotin dietary level.36  Another study concluded that a  high biotin diet improves the impaired glucose tolerance of long-term spontaneously hyperglycemic rats with non-insulin-dependent diabetes mellitus.37

According to Dr. Atkins, biotin was shown to aid in the management of blood sugar in lab experiments. In one small human study where subjects took large doses of biotin (10 mg injected 3X per week and after that 5 mg per day orally) diabetic neuropathy was halted or even reversed.  There were no ill side effects reported after a year on mega-doses of biotin.6 
Do not take these high dosages without consulting with your health care professional.

A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found Biotin to be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia.
34

Other Benefits:
Biotin may reduce hair loss in some men. It  also helps with muscle pain. It is used to treat cradle cap in infants who have a deficiency. 

Brewers Yeast
*Sal-FreeTM

Brewers yeast has a mild stabilizing effect on blood sugars because it is a rich source of minerals (especially chromium), and B vitamins. Chromium and B Vitamins help break down carbohydrates.

In one
animal study, dietary high Chromium yeast supplementation improved glucose tolerance.7  Other studies tend to support this study's conclusion.

Other Benefits:
High in protein

Carbohydrate Blockers
Low-SalTM


The active ingredient in most popular carbohydrate blocking products is a protein called phaseolamin which is extracted from white kidney beans. The protein attaches to carbohydrates, preventing them from breaking down and being absorbed by the body. 

Carbohydrates turn into sugar which releases insulin in the body so blocking carbohydrates from creating insulin should help lower blood sugar.

Carnitine
*Sal-FreeTM

Carnitine is a vitamin like substance related to the B vitamins.  It is often considered to be an amino acid because it has a chemical structure similar to that of an amino acid. 

There are many types of carnitine.  See
All about L-Carnitine for more details.

Carnitine plays a key role in glucose metabolism.  Both L-carnitine and Acetyl-L-Carnitine are effective in improving insulin-mediated glucose disposal either in healthy subjects or in type 2 diabetics.20.

Carnitine increases the breakdown of fat into energy, possibly playing a role in preventing diabetic ketoacidosis.13  It also reduces the health risks posed by poor fat metabolism associated with diabetes.11

Acetyl-L-Carnitine may prevent nerve disease associated with diabetes and sciatica.11  In one study, Carnitine, given in 1 gram injections, may reduce pain from diabetic nerve damage.18  Another study concluded that Acetyl-L-Carnitine  was effective and well tolerated in reducing pain over a 1-year period and is, therefore, a promising treatment option in patients with diabetic neuropathy.
19

Carnitine deficiencies are occasionally associated with diabetes.19

Other benefits
Lowers Cholesterol
May be  helpful in Alzheimers disease, memory difficulties, weight control, Chronic Fatigue syndrome and Fibromyalgia. See:
All about L-Carnitine

Chromium
*Sal-FreeTM

Chromium is a mineral and an essential nutrient that is involved in carbohydrate and fat metabolism.  It improves insulin's efficiency and reduces sugar cravings.

Chromium has a stabilizing effect on blood sugar and is helpful for both diabetes and hypoglycemia.11 It improves the glucose/insulin system in those with hypoglycemia, hyperglycemia, diabetes and hyperlipemia with no detectable effects on control subjects. Chromium improves insulin sensitivity through improvement in insulin binding, increased insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes.43


The average American diet is deficient in chromium and only 1 in 10 American's has enough.6,11    A deficiency causes disturbances of carbohydrate and lipid metabolism, hypoglycemia, impaired glucose tolerance, elevated cholesterol and triglycerides in blood and a decrease in HDL-cholesterol. 42  HDL is considered the good cholesterol. The higher the HDL cholesterol level, the lower the risk of coronary artery disease. 

A deficiency can also cause anxiety, fatigue, glucose intolerance (particularly in people with diabetes), inadequate metabolism of amino acids and an increased risk of arteriosclerosis.11
A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found chromium to be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia (high blood sugar).34

For a more comprehensive discussion of chromium, including various types of supplemental chromium, please read All About Chromium

Dosage Recommendations:
400-600 mcg chromium picolinate daily for diabetes according to Phyllis Bach, in her book "Prescription for Nutritional Healing".  In "Dr. Atkins' Vita-Nutrient Solution", Dr. Atkins recommends 200-600 mcg per day for insulin resistance and obesity.  For full blown diabetes or extreme obesity he recommends 600 - 1,000 mcg per day. One study noted that improvements in the glucose/insulin system were highly significant in the subjects receiving 500 micrograms twice per day with less or no significant improvements in the subjects receiving 100 micrograms twice per day after 2 and 4 months.43


Other Benefits
Athletic performance
weight loss and obesity

Lowers Cholesterol
Atypical Depression
Research: Chromium May Help Some People with Depression - and Carb Cravings

Warnings:
If you have diabetes or hypoglycemia, consult with your physician before taking any supplements containing chromium. This is particularly important for anyone taking medications for these conditions because chromium can change your requirements for these medications.

Excessive intake (tolerance depends on the individual) can lead to chromium toxicity which has been associated with dermatitis, gastrointestinal ulcers, and kidney and liver impairment.

In the past, chromium picolinate has been considered the best form of chromium supplementation because the picolinate makes the chromium more absorbable.   One animal study indicated that chromium picolinate probably generates oxidative damage of DNA and lipids and is mutagenic. The significance of those results on humans who take the supplement for prolonged periods is not known until further study is done. Since other forms of dietary chromium supplements don't appear to cause the same type of damage, it seems that use of other forms of chromium is a good idea.

Based on that study, and other considerations as noted in the link below, the Food Standards Agency in the UK advises that consumers should use other forms of chromium supplements besides chromium picolinate due to reports of genotoxicity (toxic to DNA) associated with chromium picolinate.

http://www.advisorybodies.doh.gov.uk/Com/chromium.htm
According to several studies cited by the National Institute of Health, absorption of chromium from the intestinal tract is low, ranging from less than 0.4% to 2.5%. Check the following link for a table showing the relative absorption of four common forms of chromium. 
http://www.sciencenews.org/articles/20050416/food.asp

If you are concerned about the safety of the long term use of chromium picolinate, the next best option might be chromium nicotinate which would include products called chromium GTF as well as chromium polynicotinate (ChromeMate).  According to the table presented in the Science News Article, chromium nicotinate bound to amino acids seems to be better absorbed than plain chromium nicotinate.  Vitamin C and niacin (a B vitamin), enhance chromium's absorption while calcium may inhibit absorption.


CoQ10
*Sal-FreeTM

CoQ10 is needed for normal carbohydrate metabolism. 
Animals with diabetes are coQ10 deficient.  In one study, blood sugar levels fell substantially in 31% of people with diabetes after they supplemented with 120 mg of CoQ10 per day.14

Clinical studies in Japan show that CoQ may improve glycemic control in type II diabetics.16  The results of another study show that supplementation with 200 mg of CoQ10 per day improves long-term glycaemic control in subjects with type 2 diabetes.15

Insulin and glucose indices were shown to be reduced in a  randomised, double-blind trial among patients receiving CoQ10 who were also receiving antihypertensive medication.17

Other Benefits:
Helps fatigue
Heart health
Periodontal (gum) Disease
May help reduce the toxic affect to the heart by the medications Daunorubicin and Doxorubicin which are often used in chemotherapy.  See the University of Maryland link below.
CoQ10 increases red blood cells/blood volume


Warnings:
Nausea, diarrhea or stomach upset may occur.  It may lower your blood sugar.  Consult with your doctor before using CoQ10 if you have diabetes, heart disease or allergies. The safety of CoQ10 supplementation during pregnancy and breastfeeding is unknown.  CoQ10 may enhance the effectiveness of certain blood pressure medications,  CoQ10 may decrease the effectiveness of blood-thinning medications like Warfarin.

For more information please see:


COENZYME Q10 (ubiquinone, ubidecarenone) - ORAL side effects, medical uses, and drug interactions.

University of Maryland Medical Center on Coenzyme Q10

Conjugated Linoleic Acid (CLA)
*Sal-FreeTM

There have been many animal studies that indicate that CLA may be helpful for insulin resistance. 

More human studies are needed however because to date, human studies are conflicting and some show that CLA could actually cause problems with insulin metabolism in some individuals.. One study of type 2 diabetics showed that CLA supplementation had an adverse effect on insulin and glucose metabolism.8  Another small study concluded after 8 weeks that the insulin sensitivity index improved in young, sedentary individuals however 2 out of the 10 study participants actually had worse insulin sensitivity.  they concluded that there is considerable individual variability in the response to CLA and additional studies are required.9

This information states that one study found that CLA may be helpful in managing diabetes in humans.

Fat That May Benefit Diabetics Reduces Weight, Blood Sugar

A review of peer-reviewed scientific publications found that CLA supplements in rodents reduce fat mass and increases muscle mass, but the results from 13 randomized, placebo-controlled clinical studies do not support these findings with regard to humans.  The article also states that results from animal and human studies indicate that the CLA isomer 10-trans,12-cis may have a negative impact on carbohydrate and lipid metabolism by inducing insulin resistance and hyperlipidaemia.10

Warnings:
CLA may worsen insulin resistance, carbohydrate and lipid metabolism in some individuals.  Read the information above for details.


DHEA
*Sal-FreeTM

Dehydroepiandrosterone (DHEA) is a steroid hormone produced by the adrenal glands. DHEA is a precurser to testosterone and estrogen. DHEA levels decrease with age.

Animal studies have shown that DHEA administration prevents diabetes.  A study conducted on hypoadrenal women concluded that replacement therapy with 50 mg of DHEA for 12 weeks significantly increased insulin sensitivity, thereby suggesting that DHEA replacement could have a potential impact in preventing type 2 diabetes.46
 

Other benefits:
Immune system
Hormone regulation
Infections
Weight Loss

Warnings:
Side effects may include:
Palpitations and other arrhythmias
increased growth of body hair, or hirsutism
Hair loss, especially male pattern baldness
acne

Contraindicated in patients with any cancer that is estrogen or testosterone dependent

Digestive Enzymes
*Sal-FreeTM

A lack of digestive enzymes can result in hypoglycemia.  Enzyme supplementation can also help control blood sugar in type 2 diabetes.

About half the protein that we eat gets converted to sugar.  If you lack protein or the enzymes to digest protein you can end up with low blood sugar. 

The Merck Index states that carbohydrate intolerance is caused by a lack of various digestive enzymes.  Some of the enzymes that are needed to convert complex sugars to simple sugars, if lacking, can cause hypoglycemia. You may need extra lactase, amylase, lipase or disaccharidase in order to avoid low blood sugar.


Fish Oil
*Sal-FreeTM

Fish oil is beneficial due to high levels of Omega-3 fatty acids which are polyunsaturated fatty acids.  It is thought by some that PUFAs prevent insulin resistance by increasing membrane fluidity and GLUT4 transport.21 

A meta-analysis from published clinical trials concluded that no significant changes in HbA1c (a lab test that measures the average amount of sugar in your blood over the last two to three months) percentages occurred in diabetic subjects treated with fish oil.

The same meta-analysis showed that fasting blood glucose levels were increased with borderline significance in non-insulin dependent diabetics and were significantly lowered in insulin dependent diabetics.  

Significant dose-response effects of EPA (g/day) on HbA1c and triglycerides and of DHA (g/day) on fasting blood glucose levels, HbA1c, and triglycerides were demonstrated only in non-insulin dependent diabetics.47


Yet another study found that high amounts of fish oil (2X DHA/EPA than would normally be taken to lower triglyerides)  moderately increases blood glucose and decreases insulin sensitivity in persons with type 2 diabetes without hypertriacylglycerolemia and alters carbohydrate and fat utilization in a time-dependent manner.48

Fructooligosaccharides
*Sal-FreeTM
Fructooliosaccharides, also called FOS for short, are considered a pre-biotic and are often included in products that contain probiotics.  They feed the good bacteria and allow them to thrive and grow while reducing the number of bad bacteria in the colon. 

A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found fructooligosaccharides to be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia.
34

Gymnema Sylvestre

Not acceptable for those who must avoid salicylates.
In numerous studies, Gymnema Sylvestre has shown positive results for both type 1 and type 11 diabetes.  A study of type 1 diabetic patients reduced insulin requirements and blood glucose.

Inositol
*Sal-FreeTM

Inositol is classified as a member of the vitamin B complex although it is not technically a vitamin.

Inositol may help people with Reactive Hypoglycemia or Insulin Resistance to use the insulin they produce.
http://www.sover.net/~devstar/hypogly.pdf

Other benefits:
May be helpful for the following:
bulimia
panic disorder
depression
bipolar depression
Obsessive-compulsive disorder (OCD)


Glycine
*Sal-FreeTM

Glycine is an amino acid that improves glycogen storage which helps to free up glucose for energy production.

One small study suggests that when glycine is ingested with glucose (sugar), the plasma glucose area response was attenuated by > 50% compared with the response after the ingestion of glucose alone.  The study also showed that the serum insulin concentration  was slightly elevated after the ingestion of glycine alone.12   The study suggests that the glucose clearance rate was accelerated with ingestion of glycine with glucose. For a more in-depth discussion of this study see:

The metabolic response to ingested glycine -- Gannon et al. 76 (6): 1302 -- American Journal of Clinical Nutrition

It would seem that it might be best to take glycine with a meal rather than alone if the goal is to decrease serum insulin.

More research needs to be done to determine just how helpful this supplement would be for those with blood sugar difficulties.

Other Benefits:
Retards muscle degeneration11
Repairs damaged tissues and promotes healing11
May  help prevent epileptic seizures
11

L-Glutamine
*Sal-FreeTM

 Glutamine is an amino acid.that reduces sugar cravings. 

An
animal study showed that intravenous glutamine has potential benefit as a nutrient adjuvant during clinical situations associated with insulin resistance.26

An
animal study at Duke University., examined the effects of L-glutamine on blood glucose regulation and found  a glutamine infusion into food prevented any change in the  plasma glucose and insulin levels when consumed.27

Other benefits:
In animal research it has an anti-inflammatory effect
It serves as fuel for cells lining the intestine.  It is helpful for peptic ulcers and ulcerative colitis.
Enhances mental function
Assists in maintaining the proper acid/alkaline balance in the body


Warnings
Glutamine should not be taken by persons with cirrohsis of the liver, kidney problems, Reye's syndrome or any type of disorder that can result in an accumulation of ammonia in the blood. 

L-Taurine
*Sal-FreeTM

Taurine Is an amino acid that helps stabilize blood sugar in both type 1 and type II diabetes.  It also improves cellular sensitivity to insulin.6

People with insulin dependent diabetes have low taurine levels, leading to thickened blood.  This increases their risk of heart disease.  1.5 grams per day for 3 months corrects the problem of blood viscosity within 3 months.
25

Other Benefits:
Reduces Fluid Retention by balancing sodium and potassium6
High blood pressure
seizure fighter
Helps white blood cells fire so it is beneficial for a weakened immune system
6

Linoleic Acid and Alpha Linoleic Acid
*Sal-FreeTM

These acids are considered to be in the Omega-6 family of  polyunsaturated fatty acids.  In some circumstances, polyunsaturated fatty acids may prevent insulin resistance by increasing membrane fluidity and GLUT4 transport.21

Lipoic Acid (Thioctic Acid or Alpha Lipoic Acid)
*Sal-FreeTM

Lipoic Acid is a sulfur containing vitamin like substance that is critical in glycolysis (the process in which glucose is broken down).  It is also critical for the Kreb's cycle. Glycolysis and the Krebs's cycle are two biochemical processes that are important for cellular energy production.

Alpha Lipoic Acid helps to control blood sugar levels and is helpful in the treatment of peripheral nerve damage in diabetic patients.

Alpha Lipoic Acid helps the body convert food into energy, preventing it from being stored as fat.  It also helps clean up toxins and other by products of fat metabolism.  Dr. Atkins used it in his practice to help his patients overcome metabolic resistance to losing weight.6

Alpha-lipoic acid appears to be effective and safe in the treatment of diabetic peripheral neuropathy. 5  Studies show that Lipoic Acid may be helpful in diabetic neuropathic pain. 4

Alpha Lipoic Acid is an antioxidant and acts as a protector of both water soluble and fat soluble antioxidants, including glutathione, vitamin C, vitamin E and CoEnzyme Q10. 

A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found Alpha Lipoic Acid to be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia.34

Recommended doses vary depending on the reason that you are using it and your own condition.  Dr. Atkins recommends ranges from 100-900 mg per day.  To overcome metabolic resistance to losing weight he prescribes between 300-600 mg per day.  As part of a program to treat diabetes, cancer or AIDS, he uses 600-900 mg per day. He recommends taking B1 as a supporting nutrient. 

Lipoic Acid has been used in Europe for 30 years and is considered safe. 


Other Benefits
Preliminary studies show that it significantly inhibits HIV replication. It was concluded that it may be effective in the treatment of AIDS.2,3  In addition, it may be helpful in Cancer treatment.

Warnings:
Diabetics may need to lower their insulin so it is a very good idea to keep a very close eye on insulin levels and consult with your Doctor.

Malic Acid
*Sal-FreeTM
Malic acid is a key intermediate in the production of glucose in the process of gluconeogenisis, the principal fuel for the brain. Tartaric acid, a metabolite of yeast and fungal infections inhibits the production of malic acid. If sufficient malic acid cannot be produced, the body cannot produce the sugar glucose which is the main fuel for the brain. Supplementing with malic acid can be helpful for anyone who is lacking in malic acid due to a candida or fungal infection.  For more information about malic acid see:
Malic Acid


Manganese
*Sal-FreeTM

Manganese is a trace mineral that is needed in minute amounts for protein and fat metabolism, healthy nerves, a healthy immune system and blood sugar regulation.  

According to Dr. Atkins, people with diabetes typically only have 1/2 of what is considered a normal level of manganese.and this deficiency contributes to their bodies' inability to process sugars.

Dr. Atkins found that many people don't have enough manganese as evidenced by measurements on his own patients.  Low manganese levels are more common now due to an increased diet of refined flours and sugars.  In addition, iron and calcium supplements can have an antagonistic affect on manganese.


Magnesium
*Sal-FreeTM

Magnesium is a mineral that is a catalyst in enzyme activity, especially of those enzymes used in energy production.  Magnesium plays a role in carbohydrate metabolism and a deficiency can be synonymous with diabetes.11  

How well the body metabolizes sugar is tightly linked to magnesium, making it essential to anyone with diabetes or insulin resistance.  It is most helpful for type II diabetes or insulin resistance and somewhat helpful for type I diabetes.6

A review, designed to reach a better understanding of the mechanism involved in the correlation between magnesium and insulin resistance concluded that magnesium is required for both proper glucose utilization and insulin signaling and that metabolic alterations in cellular magnesium contribute to insulin resistance.30  A Public Health review notes that recent studies suggest a potential role for magnesium in preventing diabetes. 29

One article published in "Pediatrician"  found that magnesium deficiency is the most evident disturbance of metal metabolism in diabetes.  The article also states that there is evidence that the metabolism of magnesium and other trace elements is altered in insulin dependent diabetes mellitus and that these nutrients might have a specific role in the origin and development of diabetes.28

Magnesium may prevent some of the complications of diabetes such as retinopathy and heart disease. 31

B6 is necessary in order to get magnesium into the cells.


Other benefits:
Lowers blood pressure
Helpful in fibromyalgia
Reduces birth defects if taken during pregnancy.
May help prevent cardiovascular disease, osteoporosis and certain forms of cancer. 
May reduce cholesterol levels
Assists in calcium and potassium uptake
Beneficial for cardiovascular disease
Helps mitral valve prolapse
Brain Function improvement
Migraines
Premenstrual Tension
Asthma - encourages bronchial muscles to relax
Sleep
Bruxism
helps against chemical sensitivities.


Warnings:
Can cause loose stools until your body  acclimates to it.

The body's need for magnesium is increased with the consumption of alcohol, the use of diuretics, diarrhea, the presence of fluoride or high levels of zinc or vitamin D.

The consumption of large amounts of fat, cod liver oil, calcium, vitamin D and protein decrease magnesium absorption. 

Fat soluble vitamins and foods high in oxalic acid such as almonds, chard, cocoa, rhubarb, spinach and tea also hinder absorption.
11

Melatonin
*Sal-FreeTM
The role of melatonin in insulin regulation is not well understood.   One study determined that melatonin causes a rise in blood sugars. The ability of melatonin to stimulate insulin output was dose dependent. Higher doses of melatonin caused a rise in blood sugars whereas lower levels caused no change.39

Supplementing diabetic patients with melatonin may have some benefit in controlling diabetic complications.40

Melatonin administration reduces high blood sugar and may help insulin resistance.
41

Read all about Melatonin

NAC (N-acetyl cysteine)
*Sal-FreeTM

NAC is a form of the amino acid cysteine and a powerful antioxidant. .NAC raises glutathione in the body, something that even oral supplements of glutathione itself cannot do. 

Many illnesses are directly correlated with low levels of glutathione.  Among older people, lower levels are closely associated with diabetes, arthritis and heart disease.

In a Japanese study, N-acetyl-cysteine treatment was shown to improve insulin sensitivity in women with polycystic ovary syndrome (PCOS). The study concluded that NAC may be a new treatment for the improvement of insulin circulating levels and insulin sensitivity in hyperinsulinemic patients with polycystic ovary syndrome.49



Niacin
*Sal-FreeTM

Other benefits
Lowers Cholesterol

Pancreatin
*Sal-FreeTM

Pantethine and Pantothenic Acid (B5)
*Sal-FreeTM

Pantothenic acid helps to convert fats and carbohydrates into energy.  Pantethine is the biologically active form of pantothenic acid (B5) and is the precurser to co-enzyme A.  Pantethine is made in the body from patothenic acid.

Other benefits
Lowers Cholesterol
Improves brain function, improvement of fatty liver and an increased overall energy level.

Works as an anti-inflammatory for conditions such as arthritis, allergies, lupus and psoriasis,   Helps the adrenal glands and increases omega-3 fatty acids in the body. It is know as an anti-stress vitamin.  It aids in vitamin utilization. It is needed for proper functioning of the gastro-intestinal tract.  May be helpful for anxiety and depression.

Dr. Atkins recommended between 600-900 mg per day to stabilize cholesterol and triglycerides, tame inflammation, allergies or an autoimmune problem.

It is recommended that one take a balanced B supplement if supplementing with individual B vitamins.  Taking one without balancing with others can cause imbalances.


Warnings:
Toxicity has not been reported in supplemental doses however very large doses of several grams per day can cause diarrhea.25

Polyunsaturated Fatty Acids (PUFAs)
Check each one but most are *Sal-FreeTM

PUFAs prevent insulin resistance by increasing membrane fluidity and GLUT4 transport.21

Some polyunsaturated fatty acids include the Omega-3's such as fish oil and Omega-6 such as Linoleic Acid and Alpha Linoleic Acid.


Pycnogenoll
Pycnogenol is a pine bark extract.  Clinical trials with diabetics show that is has a glucose lowering effect.
Oligomeric procyanidins of French maritime pine bark extract (Pycnogenol®) effectively inhibit alpha-glucosidase


Pyridoxine (Vitamin B6) 
*Sal-FreeTM

A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found Vitamin B6 to be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia.34

Other benefits
Reduces fluid retention

Psyllium
*Sal-FreeTM

Other Benefits
Lowers Cholesterol

Selenium
*Sal-FreeTM

A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found selenium to be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia.34

Thiamine (Vitamin B1)
*Sal-FreeTM

Important in conversion of glucose to energy.

Vanadium And Vanadyl Sulfate
*Sal-FreeTM

Vanadium is a trace mineral that dramatically helps diabetics.6   It improves insulin utilization, resulting in improved glucose tolerance.

Compounds of the trace mineral vanadium have the ability to improve glucose homeostasis and insulin resistance in
animal models of Type 1 and Type 2 diabetes mellitus.35 Another animal study found that vanadium complexes were useful in preventing and treating diabetes.33. Several reports have documented improvements in liver and muscle insulin sensitivity in a limited number of patients with Type 2 diabetes.35  Human studies show that it can greatly reduce the need for insulin and hypoglycemic medications.  It lowers blood sugar as well as the need for insulin.

Recent studies suggest that bis oxovanadium (BMOV) a more easily absorbed form of vanadyl sulfate, possessing about twice the biological activity of vanadyl sulfate.

Dr. Atkins prescribed 25-50 mg of Vanadyl Sulfate per day for his diabetic patients.


Other benefits:
 Animal studies suggest that vanadyl sulfate may help lower blood pressure in those with high blood pressure. Lowers LDL cholesterol and triglyceride levels.  May be helpful in inhibiting certain cancers.

Some body builders report that vanadyl sulfate has made their muscles bigger, harder, and more dense, and endurance athletes say that it has helped them run longer and faster.  More studies are needed to verify these effects.

A vanadium deficiency may be linked to cardiovascular and kidney disease, impaired reproductive ability and increased infant mortality.
11

Warnings:
There may be an interaction between vanadium and chromium.  One source recommends that if you supplement with both, take them at different times.  In researching interactions it appears that these findings are tentative but it was found that  in one experiment, the addition of 500 microgram of chromium/g of diet apparently made 5 micrograms of vanadium/g of diet toxic for chicks.
Interactions between essential trace and ultratrace elements  Tobacco decreases the uptake of vanadium.

Very high doses (over 100 mg per day) may cause kidney problems.  High blood levels have been linked to manic-depressive mental disorders.

Vitamin A (Retinol)
*Sal-FreeTM

A study based on 52 healthy people found that those who consumed more than 10,000 IU of Vitamin A per day metabolized glucose better than those who took in less than 8,000 IU.  It was concluded that vitamin A helps  to get blood sugar into the body's cells.
1

Other benefits:
Acne and other skin disorders
Vision - night blindness
May help heal gastrointestinal ulcers
Wound healing
Immune system support
Wrinkle reducer when applied topically


Warnings
Taking large amounts of Vitamin A, (over 100,000 IU per day) over a long period of time can be toxic to the body.  If you are pregnant or have liver disease, do not take over 10,000 IU per day.  Excessive intake during pregnancy has been linked to birth defects.

Vitamin B6
*Sal-FreeTM

See Pyridoxine

Vitamin C
*Sal-FreeTM

A study designed to determine the effect of vitamin C supplementation on blood sugar and antioxidative status in Types II diabetes mellitus patients found that vitamin C may have a beneficial effect in diabetes mellitus patients on both glycemic control and antioxidant status.38

A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found vitamin C o be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia.34

Warnings:
An article in the American Journal of Clinical Nutrition observed that a high vitamin C intake from supplements is associated with an increased risk of cardiovascular disease mortality in postmenopausal women with diabetes.
Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes?

Vitamin D
*Sal-FreeTM

Supplementation is preventative for type 1 diabetes.  Low levels are associated with insulin resistance and supplementation is useful for those with type 2 diabetes who are low in vitamin D.


Vitamin E
*Sal-FreeTM

 Double blind studies show that Vitamin E improves glucose tolerance in people with type 2 diabetes.23,24 People who have low blood levels of Vitamin E are more likely to develop type 2 diabetes.22  Vitamin E prevents blood from clotting too fast and has other effects that protect diabetics' blood vessels from damage.  It also protects animals from diabetic cataracts.

A double blind study found that a group of patients with atypical depression had significant improvement in depression and carbohydrate cravings with the supplementation of chromium picolinate.44

A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found vitamin E to be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia.34

It may require 3 or more months of supplementation for benefits to become apparent.  The most common amount used is 900IU per day.25

Zinc
*Sal-FreeTM
 

Zinc is a mineral that is involved in virtually all aspects of insulin metabolism. 

Supplementation has been shown to improve insulin levels in both type I and type II diabetes.32 Increased urinary loss of zinc is a commonly encountered feature of diabetes.28

A survey of 685 Italian herbalists, conducted by the Atherosclerosis Research Centre at the  University of Bologna found zinc to be one of the 10 most frequently recommended dietary supplements for use in controlling glycemia.34

 


References
1.Facchini F, Coulston AM, Reaven GM, Relation between dietary vitamin intake and resistance to insulin-mediated glucose disposal in healthy volunteers. Am J Clin Nutr. 1996 Jun;63(6):946-9
Entrez PubMed Abstract

2. A. Baur, et al, "Alpha -Lipoic Acid is an Effective Inhibitor of Human Immune-Deficiency Virus (HIV1) Replication", Klin Wochenschr. 1991 Oct 2;69(15):722-4
Entrez PubMed Abstract

3.Y.J. Suzuki, B.B. Aggarwal, and L. Packer, "Alpha Lipoic Acid is a Potent Inhibitor of NF-kB Activation in Human T Cells", Biochem Biophys Res Commun, 1992 Dec 30;189(3):1709-15.
Entrez PubMed Abstract

4. Braune S., "Evidence-based pharmacotherapy of neuropathic pain syndromes", MMW Fortschr Med. 2004 Dec 9;146(50):49-51.
Entrez PubMed Abstract

5. Negrisanu G, Rosu M, Bolte B, Lefter D, Dabelea D., "Effects of 3-month treatment with the antioxidant alpha-lipoic acid in diabetic peripheral neuropathy.", Rom J Intern Med. 1999 Jul-Sep;37(3):297-306.
Entrez PubMed Abstract

6. Robert C. Atkins,  "Dr. Atkins' Vita-Nutrient Solution : Nature's Answer to Drugs"

7.  Guan X, Matte JJ, Ku PK, Snow JL, Burton JL, Trottier NL., "High chromium yeast supplementation improves glucose tolerance in pigs by decreasing hepatic extraction of insulin.", J Nutr. 2000 May;130(5):1274-9.
Entrez PubMed Abstract

8.  Moloney F, Yeow TP, Mullen A, Nolan JJ, Roche HM., "Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus.", Am J Clin Nutr. 2004 Oct;80(4):887-95.
Entrez PubMed Abstract

9.  Eyjolfson V, Spriet LL, Dyck DJ, "Conjugated linoleic acid improves insulin sensitivity in young, sedentary humans", .Med Sci Sports Exerc. 2004 May;36(5):814-20.
Entrez PubMed Abstract

10.  Haugen M, Alexander J., "Can linoleic acids in conjugated CLA products reduce overweight problems?",Tidsskr Nor Laegeforen. 2004 Dec 2;124(23):3051-4.
Entrez PubMed Abstract

11.  Phyllis A. Balch, CNC, "Prescription for Nutritional Healing, A practical A-To-Z Reference to Drug-Free Remedies Using Vitamins Minerals, Herbs and Food Supplements"

12. Gannon MC, Nuttall JA, Nuttall FQ., "The metabolic response to ingested glycine.", Am J Clin Nutr. 2002 Dec;76(6):1302-7
Entrez PubMed Abstract
For a more in-depth discussion see:
The metabolic response to ingested glycine -- Gannon et al. 76 (6): 1302 -- American Journal of Clinical Nutrition

13.  Michael Murray, N.D., and Joseph Pizzorno, N.D., "The Encyclopedia of Natural Medicine".

14.  Shigeta Y, Izumi K, Abe H.. "Effect of coenzyme Q7 treatment on blood sugar and ketone bodies of diabetics", J. Vitaminology 1966; 12:293-98.

15.  Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD., "Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes.", Eur J Clin Nutr. 2002 Nov;56(11):1137-42.
Entrez PubMed Abstract

For more in-depth information see:
Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes

16.  McCarty MF., "Can correction of sub-optimal coenzyme Q status improve beta-cell function in type II diabetics?", Med Hypotheses. 1999 May;52(5):397-400.
Entrez PubMed Abstract

17.  Singh RB, Niaz MA, Rastogi SS, Shukla PK, Thakur AS., "Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease.", J Hum Hypertens. 1999 Mar;13(3):203-8.
Entrez PubMed Abstract

18.  Onofrj M.,. Fulgente T., Mechionda D. et al, "L-acetylcarnitine as a New Therapeutic Approach for Peripheral Neuropathies with pain", Int J Clin Pharmacol Res. 1995;15(1):9-15.
Entrez PubMed Abstract

19.  De Grandis D, Minardi C., "Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy. A long-term, randomised, double-blind, placebo-controlled study."., Drugs R D. 2002;3(4):223-31.
Entrez PubMed Abstract

20. Mingrone G, "Carnitine in type 2 diabetes.",  Ann N Y Acad Sci. 2004 Nov;1033:99-107.
Entrez PubMed Abstract

21.  Manco M, Calvani M, Mingrone G., "Effects of dietary fatty acids on insulin sensitivity and secretion.", Diabetes Obes Metab. 2004 Nov;6(6):402-13
Entrez PubMed Abstract

22.  Salonen JT, Nyssonen K, Tuomaninen T-P, et al, "IIncreased risk of non-insulin dependent diabetes mellitus at low plasma vitamin E concentrations: a four year follow up study in men.", BMJ. 1995 Oct 28;311(7013):1124-7.
Entrez PubMed

23. Paolisso G, D'Amore A, Giugliano D, Ceriello A, Varricchio M, D'Onofrio F., "Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin-dependent diabetic patients.", Am J Clin Nutr. 1993 May;57(5):650-6.
Entrez PubMed

24. Paolisso G, D'Amore A, Galzerano D, Balbi V, Giugliano D, Varricchio M, D'Onofrio F.,  "Daily vitamin E supplements improve metabolic control but not insulin secretion in elderly type II diabetic patients." Diabetes Care. 1993 Nov;16(11):1433-7.
Entrez PubMed

25.  Skye Lininger, D.C., Editor in Chief, Jonathan Wright, M.D., Steve Austin, N.D., Donald Brown, N.D. and Alan Gaby, M.D. "The Natural Pharmacy"

26.  Borel MJ, Williams PE, Jabbour K, Levenhagen D, Kaizer E, Flakoll PJ., "Parenteral glutamine infusion alters insulin-mediated glucose metabolism.", JPEN J Parenter Enteral Nutr. 1998 Sep-Oct;22(5):280-5.
Entrez PubMed

27.Ballard TC, Farag A, Branum GD, Akwari OE, Opara EC., "Effect of L-glutamine supplementation on impaired glucose regulation during intravenous lipid administration.", Nutrition. 1996 May;12(5):349-54.
Entrez PubMed

28.  Tuvemo T, Gebre-Medhin M., "The role of trace elements in juvenile diabetes mellitus.", Pediatrician. 1983-85;12(4):213-9.
Entrez PubMed

29.  Schulze MB, Hu FB., "PRIMARY PREVENTION OF DIABETES: What Can Be Done and How Much Can Be Prevented?", Annu Rev Public Health. 2005 Apr 21;26:445-467.
Entrez PubMed

30.  Takaya J, Higashino H, Kobayashi Y., "Intracellular magnesium and insulin resistance.", Magnes Res. 2004 Jun;17(2):126-36.
Entrez PubMed

31.  J.R. White and R.K. Campbell, "Magnesium and Diabetes: A Review", Ann Pharmacother 27 (1993), 775-80
Entrez PubMed

32.  S.M. Hegazi et al, "Effect of zinc Supplementation on Serum Glucose, Insulin, Glucagon, Clucose-6-Phosphatase, and Mineral Levels in Diabetics,," J. Clin. Biochem Nutr 12 (1992): 209-15

33. Sakurai H., "Therapeutic potential of vanadium in treating diabetes mellitus", .Clin Calcium. 2005 Jan;15(1):49-57.
Entrez PubMed

34.  Cicero AF, Derosa G, Gaddi A., "What do herbalists suggest to diabetic patients in order to improve glycemic control? Evaluation of scientific evidence and potential risks", Acta Diabetol. 2004 Sep;41(3):91-8.
Entrez PubMed

 35.  Srivastava AK, Mehdi MZ., "Insulino-mimetic and anti-diabetic effects of vanadium compounds.", Diabet Med. 2005 Jan;22(1):2-13.
Entrez PubMed

36.  Tsunoda K, Osada K, Komai M, Zhang H, Morimoto K, Suzuki H, Furukawa Y.. "Effects of dietary biotin on enhanced sucrose intake and enhanced gustatory nerve responses to sucrose seen in diabetic OLETF rat.". J Nutr Sci Vitaminol (Tokyo). 1998 Apr;44(2):207-16.
Entrez PubMed

37.  Zhang H, Osada K, Maebashi M, Ito M, Komai M, Furukawa Y.,  "A high biotin diet improves the impaired glucose tolerance of long-term spontaneously hyperglycemic rats with non-insulin-dependent diabetes mellitus.", J Nutr Sci Vitaminol (Tokyo). 1996 Dec;42(6):517-26
Entrez PubMed

38.  Park HS, Lee YM., "[Effect of vitamin C supplementation on blood sugar and antioxidative status in types II diabetes mellitus patients]", Taehan Kanho Hakhoe Chi. 2003 Apr;33(2):170-8.
Entrez PubMed

39.  Fabis M, Pruszynska E, Mackowiak P., "In vivo and in situ action of melatonin on insulin secretion and some metabolic implications in the rat.", Pancreas. 2002 Aug;25(2):166-9.
Entrez PubMed

40.  Paskaloglu K, Sener G, Ayangolu-Dulger G., "Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum.", Eur J Pharmacol. 2004 Sep 24;499(3):345-54.
Entrez PubMed

41.  Nishida S, Segawa T, Murai I, Nakagawa S., "Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity.", J Pineal Res. 2002 Jan;32(1):26-33.
Entrez PubMed

42. Terpilowska S, Zaporowska H.," [The role of chromium in cell biology and medicine]",  Przegl Lek. 2004;61 Suppl 3:51-4.
Entrez PubMed

43.  Anderson RA., "Nutritional factors influencing the glucose/insulin system: chromium.", J Am Coll Nutr. 1997 Oct;16(5):404-10.
Entrez PubMed

44. Docherty JP, Sack DA, Roffman M, Finch M, Komorowski JR., "A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving.", J Psychiatr Pract. 2005 Sep;11(5):302-14.
Entrez PubMed

45. Vincent JB., "The potential value and toxicity of chromium picolinate as a nutritional supplement, weight loss agent and muscle development agent.", Sports Med. 2003;33(3):213-30.
Entrez PubMed

46. Dhatariya K, Bigelow ML, Nair KS., "Effect of dehydroepiandrosterone replacement on insulin sensitivity and lipids in hypoadrenal women.", Diabetes. 2005 Mar;54(3):765-9
Entrez PubMed

47.  CE Friedberg, MJ Janssen, RJ Heine and DE Grobbee,  "Fish oil and glycemic control in diabetes. A meta-analysis", Diabetes Care, Vol 21, Issue 4 494-500, Copyright © 1998 by American Diabetes Association
Fish oil and glycemic control in diabetes. A meta-analysis -- Friedberg et al. 21 (4): 494 -- Diabetes Care

48.  Ingrid L Mostad, Kristian S Bjerve, Marit R Bjorgaas, Stian Lydersen and Valdemar Grill, "Effects of n–3 fatty acids in subjects with type 2 diabetes: reduction of insulin sensitivity and time-dependent alteration from carbohydrate to fat oxidation 1,3", American Journal of Clinical Nutrition, Vol. 84, No. 3, 540-550, September 2006
Effects of n-3 fatty acids in subjects with type 2 diabetes: reduction of insulin sensitivity and time-dependent alteration from carbohydrate to fat oxidation -- Mostad et al. 84 (3): 540 -- American Journal of Clinical Nutrition

49.Fulghesu AM, Ciampelli M, Muzj G, Belosi C, Selvaggi L, Ayala GF, Lanzone A.,  "N-acetyl-cysteine treatment improves insulin sensitivity in women with polycystic ovary syndrome.", Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore, Roma, Italy.
N-acetyl-cysteine treatment improves insulin sensi...[Fertil Steril. 2002]
 

Before taking any supplements, consult with your health care provider. The information presented here is not intended to diagnose, treat, cure or prevent any disease. We do not accept any responsibility for the use or misuse of any of the information contained herein.

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In an effort to help end animal testing, we only list cosmetics and supplements that have been produced by companies that do not use animal testing in their ingredients or products unless it is required by law.

For further information on animal testing please see:
Animal testing.  The basics and how to avoid buying products that are tested on animals.
 

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