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Read about blood sugar, cholesterol, homemade cosmetics, find salicylate free strategies and more.



Low Carbohydrate Information

Low Carbohydrate Cook Books

Low Carbohydrate, Low Fat Cookbooks.

Low Carb Products with No Sugar Alcohols

Supplements for Blood Sugar Control

Cruelty Free Supplements

Cruely Free Cosmetics
 


Low Carbohydrate, Low Fat Cookbooks.

cover
Dr. Atkins' Vita-Nutrient Solution : Nature's Answer to Drugs


PDR for Nutritional Supplements



The PDR Family Guide to Nutritional Supplements : An Authoritative A-to-Z  

The Magazine - Pdr For Nutritional Supplements


A Practical A-Z Reference to Drug-Free Remedies Using Vitamins, Minerals, Herbs, and Food Supplements



The Insulin-Resistance Diet : How to Turn Off Your Body's Fat-Making Machine



Blood Sugar Blues : Overcoming the Hidden Dangers of Insulin Resistance
by Miryam Ehrlich Williamson, R. Paul St. Amand M.D.


Insulin Resistance: A Medical Dictionary, Bibliography, And Annotated Research Guide To Internet References

Magnesium and the Insulin Resistance Syndrome (Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, 1088)



Insulin Resistance and Cardiovascular Disease


Syndrome X: The Complete Nutritional Program to Prevent and Reverse Insulin Resistance



The Insulin Factor: Can't Lose Weight? Can't Concentrate? Can't Resist Sugar? Could Syndrome X Be Your Problem



Balance Your Blood Sugar Naturally to Beat Disease, Lose Weight, Gain Energy, and Feel Great


The Low Blood Sugar Handbook: You Don't Have to Suffer....



The Low Blood Sugar Cookbook: Sugarless Cooking for Everyone



What Makes My Blood Glucose Go Up...And Down? And 101 Other Frequently Asked Questions About Your Blood Glucose Levels



LOW BLOOD SUGAR Hypoglycemia: The 20th Century Epidemic?



101 Tips For Improving Your Blood Sugar



Reactive Hypoglycemia - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References


Preventing Reactive Hypoglycemia: The Great Medical Dilemma


The New Glucose Revolution: The Authoritative Guide to the Glycemic Index--the Dietary Solution for Lifelong Health



Atkins Diabetes Revolution : The Groundbreaking Approach to Preventing and Controlling Type 2 Diabetes



The G.I. Handbook : How the Glycemic Index Works

 


New Glucose Revolution Guide to Living Well with Polycystic Ovary Syndrome

Hyperinsulinemia, Not Ovaries, at Core of Polycystic Ovary Syndrome. : An article from: Family Practice News

Metformin Appears Effective in Teens With Polycystic Ovary Syndrome. (Brief Article) : An article from: Family Practice News

Endocrine ills in Polycystic Ovary Syndrome patients' sisters, mothers. (At Risk for Type 2 Diabetes). : An article from: Internal Medicine News

Obese Women With Polycystic Ovary Syndrome Face Higher Sleep Apnea Risk. : An article from: OB GYN News
 


Encyclopedia of Natural Medicine

Sleep Apnea and Disorders of glucose metabolism

Diet, Exercise Dramatically Delay Type 2 Diabetes

Exercise Equipment

 

Diet, Exercise Dramatically Delay Type 2 Diabetes

CDC - Exercise can delay onset of diabetes

Exercise Reduces Diabetes by Reducing Insulin Resistance
 


The Healing Power of Exercise : Your Guide to Preventing and Treating Diabetes, Depression, Heart Disease, High Blood Pressure, Arthritis, and More


The Diabetic Athlete
 


Handbook of Exercise in Diabetes


The Fitness Book: For People With Diabetes


How blood sugar works

CDC's Diabetes Program - Publications & Products - Take Charge of Your Diabetes - Glossary


Insulin Receptors in Brain Tied to Appetite and Weight Gain


Leptin May Control Sweet Tooth


Diabetes breakthrough
Toronto scientists cure disease in mice

National Diabetes Information Clearinghouse

Diabetes Dictionary

Type 2 Diabetes In the Genes

NIDDK Clearinghouses Publications Catalog
 

 

Diseases,  Medical Conditions and Deficiencies that are Associated with Blood Sugar and Insulin Control

There are a surprising number of illnesses, conditions and vitamin and mineral deficiencies that are associated with blood sugar and insulin control. For example, if you have an H. Pylori bacterial infection, studies show that you will be able to better control your blood sugars if you get rid of the infection.  According to some studies, you may be able to alleviate some of the symptoms of Polycystic Ovary Syndrome by dealing with your insulin resistance. 

High glucose levels can contribute to aging due to a destructive process known as glycosylation, also called nonenzymatic glycation, in which glucose molecules bind to proteins and interfere with their function. People with diabetes have an increased rate of protein glycosylation and this plays a major part in their increased risk of atherosclerosis and contributes to many other diseases.

Magnesium and zinc deficiencies are commonly seen in diabetics and blood sugar control will get better in some individuals with supplementation of these minerals.  These are just a few of the many factors that can affect your blood sugars.

Blood sugar control problems often run in families and can exist for many years before one becomes aware of them. You may not connect irritability with low blood sugar or an unusual feeling of hunger with hypoglycemia.  For those who have hypoglycemia, if you control your blood sugars now, you will be less likely to develop diabetes.  For those with diabetes, if you maintain good control over your blood sugars, you will avoid or at the very least, postpone the many devastating complications of diabetes.  For help in controlling your blood sugars, speak to your doctor.  You may also be interested in supplements that help control blood sugar.

Understanding the factors that affect blood sugar control will help you maintain better control. 

 
Biotin
A deficiency can cause high blood sugar.  For more information please see:
Supplements for blood sugar control - Biotin

Boron
A lack of boron may increase insulin resistance.
Hyperinsulinemia in Rats During Dietary Vitamin D (Vitd) and Boron Deprivation Is Ameliorated, But Not Corrected, by Improved Vitd Status

Caffeine
Caffeine has been shown to reduce insulin sensitivity independent of obesity, type 2 diabetes or exercise.41

Another study concluded that
The effects of insulin are greatly enhanced with the use of caffeine because of it's ability to block the enzyme phosphodiesterase.

http://www.sover.net/~devstar/hypogly.pdf

Carnitine
Carnitine deficiencies are occasionally associated with diabetes.23

For more information about carnitine see:
Supplements for Blood Sugar Control - Carnitine

Candida (Yeast Infection)
It is well known that those with diabetes are more prone to candida infections.  This is thought to be due to a compromised immune system and/or higher glucose levels in the blood.

The Division of Bacterial and Mycotic Diseases at the Centers for Disease Control and Prevention conducted a prospective, active population-based surveillance for candidemia (defined as any Candida species isolated from blood).  They determined that the average incidence of candida  infection was 7 in 100,00, however the rate of infection for adult diabetics was 4 times higher or 28 in 100,000.33

A study of 78 diabetic females and 88 healthy controls determined that there is a significant link between high blood sugars and vulvo-vaginal candidiasis.31  A candida infection of the nail bed is more prevalent in diabetics.29 and candida colonization of the skin and nail bed is significantly associated with diabetes.30  Another study found that oral candida was more prevalent in diabetics.
32


Cholesterol
There is an association between high cholesterol and insulin resistance.  According to the National Diabetes Information Clearinghouse (a division of the National Institutes of Health), many people with insulin resistance and high blood glucose have high LDL (bad) blood cholesterol levels, low HDL (good) cholesterol levels and high levels of triglycerides (another fat in the blood),
Insulin Resistance and Pre-Diabetes

This is not surprising considering that an enzyme, (HMGCoA) controls the production of cholesterol in your liver and the two main hormones that control the release of the enzyme (HMGCoA) are glucagon and insulin.  Glucagon inhibits the enzyme, and insulin activates it.  The Statin drugs (cholesterol controlling medications) control cholesterol by inhibiting this enzyme.

For more information please see:
Cholesterol, Triglycerides and Heart Support

Depression
One study concluded that Depression appears to increase the risk of developing diabetes by 23% in younger adults.26

The prevalence of depression in diabetic patients may be as high as 30%.28  An article in the Journal of Indian Medicine noted that diabetics often have depression and that prompt treatment of depression has beneficial effects on glycaemic control for diabetic patients.27 


Diabetes
There are 2 main types of diabetes, type 1 (insulin dependent diabetes mellitus IDDM) and  type 2 (non-insulin dependent diabetes NIDDM).  Type 1 makes up only 5-10 percent of the diabetic population, the rest are type 2 diabetics.   

Type 1 is an autoimmune disease where the body's immune system attacks and destroys the insulin producing cells in the pancreas.  Some experts believe this immune response may be the result of a virus.

In type 2 diabetes, the body does produce insulin but not enough.  The body's cells also become resistant to insulin.  For a detailed, technical  explanation of type 2 diabetes see:  Deconstructing Type 2 diabetes

Many people have type 2 diabetes and don't even know it.  Take the American Diabetes Association
Diabetes Risk Test to assess your risk of getting diabetes..

According to the American Diabetes Association, diabetes is the 6th leading cause of death in the United States.  It is a serious disease with many life threatening side effects so it is well worth considering all of your options in order to normalize blood sugars and minimize damage to your body.

Drugs that affect blood sugar
Besides the drugs that one takes intentionally to affect their blood sugar, there is a large list of drugs that will affect your blood sugar.  39, 40

Some of the medications associated with hyperglycemia (high blood sugar) are as follows:

Thiazide Diuretics, Centrally Acting Alpha-Blockers, Beta-blockers, Calcium-Channel Blockers, Minoxidil, Diazoxide, Corticosteroids, cyclosporine, phenytoin, oral contraceptives and sex hormones, Nicotinic Acid and Niacin, Phenothiazines. lithium, thyroid hormone, Beta-Adrenergic Agonists and misc. drugs.  See the following for references to each drug.
Drug-induced Disorders of Glucose Tolerance -- Pandit et al. 118 (7): 529 -- Annals of Internal Medicine

Drugs that may cause hypoglycemia (low blood sugar)
 

Helicobacter Pylori (H. Pylori)

H. Pylori is a bacterial infection that causes gastritis and can cause ulcers.  It has been shown to run in families. 

Both obesity and type II diabetes may be associated with an increased incidence of H. pylori-colonization.2  It has been shown that it may contribute to hypoglycemia.14    One study stated that H. Pylori may lead to lower glucose concentrations in women and should be considered when interpreting plasma glucose concentrations bordering on diabetes.15

Eradication of H. Pylori is shown to improve hypoglycemia.14
 

Fibromyalgia
It is not uncommon for people with fibromyalgia to have blood sugar disorders such as  reactive hypoglycemia (a precurser to type 2 diabetes) or diabetes.

Devin Starlanyl, a physician who has fibromyalgia writes about reactive
hypoglycemia and fibromyalgia.
You may also wish to read her article about Reactive Hypoglycemia.

One study concluded that Fibromyalgia is a common finding in patients with types 1 and 2 diabetes.  They hypothesize that Fibromyalgia might be prevented  by improved control of blood glucose levels.21 Another study noted that there was a clinical association between obesity, diabetes mellitus and fibromyalgia.22

Heart Disease
Strong connection between diabetes and heart disease

Diabetes is considered a major risk factor for coronary artery disease.  According to the American Diabetes Association, people with diabetes are 2 to 4 times more likely to develop heart disease.  They think this is due to an upset balance between HDL and LDL cholesterol levels.

Other articles of interest
Supplements for lowering your cholesterol and triglycerides and increasing your good cholesterol

National Women's Health Report: The diabetes-heart disease connection

Scientists Report New Findings On The Connection Between Diabetes And Heart Disease And Stroke

Hypoglycemia
Hypoglycemia is considered present when blood glucose levels are less than 50 mg/dL Hypoglycemia can sometimes occur in persons with diabetes due to the medication that they take to control their diabetes or to exercise in diabetics but here, we will be talking about other types of hypoglycemia. 

Causes:
Hypoglycemia can be idiopathic (cause unknown) or it can be caused by GI surgery, liver disease, a pancreatic tumor, pregnancy, renal glycosuria (glucose is abnormally eliminated in the urine due to improper functioning of the kidney tubules), Ketotic hypoglycemia of childhood, adrenal insufficiency, hypopituitarism, digestive enzyme deficiency, large tumors (eg, mesenchymal tumors, epithelial tumors, endothelial tumors), sepsis and starvation.

Symptoms:
The symptoms listed here are symptoms seen in all types of hypoglycemia, including acute hypoglycemia as seen in diabetics.

Shakiness, anxiety, nervousness, tremor, palpitations, tachycardia (fast pulse), sweating, feeling of warmth, pallor (paleness), coldness, clamminess, dilated pupils, hunger, borborygmus (gurgling, rumbling, or growling noise from the abdomen), nausea, vomiting, abdominal discomfort, abnormal thinking, impaired judgment, nonspecific dysphoria (an emotional state characterized by feeling ill, anxiety, depression or unease), moodiness, depression, crying, fear of dying, negativism, irritability, belligerence, combativeness, rage, personality change, emotional lability (instability), fatigue, weakness, apathy, lethargy, daydreaming, sleep disturbance including insomnia, confusion, amnesia (loss of memory), dizziness, delirium, staring, "glassy" look, blurred vision, double vision, difficulty speaking, slurred speech, ataxia, incoordination, sometimes mistaken for "drunkenness", focal or general motor deficit, paralysis, hemiparesis (weakness of one side of the body), paresthesias (abnormal sensations such as numbness, prickling, or "pins and needles."), headache, stupor, coma, abnormal breathing, generalized or focal seizures

Drugs that may be related to hypoglycemia:  salicylates, oral hypoglycemics, sulfonamide, phenylbutazone, insulin, bishydroxy coumarin,  p-aminobenzoic acid, propoxyphene, haloperidol, stanozolol, ethanol, hypoglycin, carbamate insecticide, disopyramide, isoniazid, methanol, methotrexate, pentamidine, sulfonamide, tricyclic antidepressants, cytotoxic agents, organophosphates, propranolol plus ethanol, didanosine, chlorpromazine, quinine, sulfa drugs, fluoxetine, sertraline, fenfluramine, trimethoprim, 6-mercaptopurine, thiazide diuretics, thioglycolate, tremetol, ritodrine, disodium ethylenediaminetetraacetic acid (EDTA), clofibrate, angiotensin converting enzyme (ACE) inhibitors, and lithium.
 

Infection/Inflammation
One study found a correlation between low grade infections and insulin resistance. Their conclusions:
"Pathogen burden showed the strongest association with insulin resistance, especially with enteroviruses and C. pneumoniae seropositivity. We hypothesize that exposure to multiple pathogens could cause a chronic low-grade inflammation, resulting in insulin resistance."
 Burden of Infection and Insulin Resistance in Healthy Middle-Aged Men -- Fernández-Real et al. 29 (5): 1058 -- Diabetes Care


Another study states that some components of the insulin resistance syndrome have been related to inflammatory markers and that chronic sub-clinical inflammation is part of insulin resistance syndrome.42

Low Grade Chronic Inflammation in Women with Polycystic Ovarian Syndrome -- Kelly et al. 86 (6): 2453 -- Journal of Clinical Endocrinology & Metabolism

Insomnia
According to the authors of the Encyclopedia of Natural Medicine, their experience in clinical practice has shown that nocturnal hypoglycemia (low night-time blood glucose level) is an important cause of sleep-maintenance-insomnia. 

When there is a drop in blood glucose level, it causes the release of  hormones that regulate glucose levels such as adrenaline, glucagon, cortisol and growth hormones which signal the brain that it is time to eat.  According to the authors of the
Encyclopedia of Natural Medicine, good bed-time snacks that keep blood sugar levels steady throughout the night are complex carbohydrates such as oatmeal and other grains.

It is known that short term sleep restriction results in glucose intolerance.  In a long term prospective study (10 years), 70,000 non-diabetic women were followed.  In evaluating the self-reported data from these women, researchers determined that long and short (5 hours or less) sleep durations were associated with an increased risk of diabetes diagnosis.17

Manganese
Deficiency and blood sugar regulation

Manganese is a trace mineral that is needed in minute amounts for protein and fat metabolism, healthy nerves, a healthy immune system and blood sugar regulation.10 

According to Dr. Atkins, people with diabetes typically only have 1/2 of what is considered a normal level of manganese and this deficiency contributes to their bodies' inability to process sugars.

Dr. Atkins found that many people don't have enough manganese as evidenced by measurements on his own patients.  Low manganese levels are more common now due to an increased diet of refined flours and sugars.  In addition, iron and calcium supplements can have an antagonistic affect on manganese.

Magnesium Deficiency and diabetes
Magnesium is a mineral that is a catalyst in enzyme activity, especially of those enzymes used in energy production.  Magnesium plays a role in carbohydrate metabolism and a deficiency can be synonymous with diabetes.9  

How well the body metabolizes sugar is tightly linked to magnesium, making it essential to anyone with diabetes or insulin resistance.  It is most helpful for type II diabetes or insulin resistance and somewhat helpful for type I diabetes.10

A review, designed to reach a better understanding of the mechanism involved in the correlation between magnesium and insulin resistance concluded that magnesium is required for both proper glucose utilization and insulin signaling and that metabolic alterations in cellular magnesium contribute to insulin resistance.12  A Public Health review notes that recent studies suggest a potential role for magnesium in preventing diabetes. 11

One article published in "Pediatrician"  found that magnesium deficiency is the most evident disturbance of metal metabolism in diabetes.  The article also states that there is evidence that the metabolism of magnesium and other trace elements is altered in insulin dependent diabetes mellitus and that these nutrients might have a specific role in the origin and development of diabetes.3

Magnesium may prevent some of the complications of diabetes such as retinopathy and heart disease. 13

B6 is necessary in order to get magnesium into the cells.

Other benefits:
Lowers blood pressure
Helpful in fibromyalgia
Reduces birth defects if taken during pregnancy.
May help prevent cardiovascular disease, osteoporosis and certain forms of cancer. 
May reduce cholesterol levels
Assists in calcium and potassium uptake
Beneficial for cardiovascular disease
Helps mitral valve prolapse
Brain Function improvement
Migraines
Premenstrual Tension
Asthma - encourages bronchial muscles to relax
Sleep
Bruxism
helps against chemical sensitivities.

Warnings:
Can cause loose stools until your body gets used  to it.

The body's need for magnesium is increased with the consumption of alcohol, the use of diuretics, diarrhea, the presence of fluoride or high levels of zinc or vitamin D.

The consumption of large amounts of fat, cod liver oil, calcium, vitamin D and protein decrease magnesium absorption.  Fat soluble vitamins and foods high in oxalic acid such as almonds, chard, cocoa, rhubarb, spinach and tea also hinder absorption.9

Melatonin
The role of melatonin in human insulin regulation is poorly understood however one
animal study determined that melatonin caused a rise in blood sugars. The ability of melatonin to stimulate insulin output was dose dependent. Higher doses of melatonin caused a significant rise in blood sugars whereas lower levels caused no change. 19

One study found that giving diabetic patients melatonin supplementation may have some benefit in controlling diabetic complications.18

Another
animal study reported that long-term melatonin administration reduces high blood sugar and may help insulin resistance.20

Metabolic Syndrome (Syndrome X)
Metabolic Syndrome is a set of risk factors in an individual that predisposes them to several illnesses, including type 2 diabetes and heart disease.  Syndrome X is closely associated with insulin resistance.  Low magnesium and high calcium are commonly seen in this syndrome.

Syndrome X is characterized by central obesity (excessive fat tissue in and around the abdomen), insulin resistance or glucose intolerance (the body can't properly utilize insulin),
cholesterol disorders (usually high triglycerides and low HDL cholesterol), high blood pressure, high fibrinogen or plasminogen activator inhibitor [–1] in the blood and elevated high-sensitivity C-reactive protein in the blood.

A long term study concluded that Cardiovascular disease and all-cause mortality are increased in men with the metabolic syndrome.34

Another study has found that Sleep apnea is a manifestation of the metabolic syndrome.35

Syndrome X may be identified by the presence of three or more of these components:

Central obesity as measured by waist circumference:
Men — Greater than 40 inches
Women — Greater than 35 inches
Fasting blood triglycerides greater than or equal to 150 mg/dL
Blood HDL cholesterol:
Men — Less than 40 mg/dL
Women — Less than 50 mg/dL
Blood pressure greater than or equal to 130/85 mmHg
Fasting glucose greater than or equal to 110 mg/dL

Night Eating Syndrome (NES)
Night Eating Syndrome is characterized by eating 50% or more of daily calories after dinner and by getting up during the night to eat.  It has recently received new interest and is currently being studied.  It is hypothesized to be caused by a disturbed circadian eating rythym (the body's 24 hour clock).  Those who have it, often have a relative with the syndrome.

One study found that the strong association between glucose and insulin was damaged in those participants whose eating patterns mimicked those of Night Eating Syndrome.  It was suggested that Night Eating Syndrome eating patterns lead to the impairment of insulin response. 16

Some people who wake up during the night and feel that they must eat something may have
insomnia that is caused hypoglycemia.  According to the authors of the Encyclopedia of Natural Medicine, their experience in clinical practice has shown that nocturnal hypoglycemia (low night-time blood glucose level) is an important cause of sleep-maintenance-insomnia. 

Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome (PCOS), is a hormonal disturbance experienced by women of reproductive age. It is the leading cause of infertility. The hormonal disturbance often seems to be linked to the way the body handles insulin.  Those with Polycystic Ovary Syndrome are more likely to develop diabetes.

Polycystic Ovary Syndrome is associated with insulin resistance and hyperinsulinemia (high insulin).  Decreasing ones insulin resistance appears to be helpful in treating the symptoms of Polycystic Ovary Syndrome.23.

Some of the symptoms of Polycystic Ovary Syndrome are:
infertility - caused by inability to ovulate, lack of menses (periods),. facial and or body hair (hirsutism), acne and/or oily skin, obesity and insulin resistance.



One study found that women with the polycystic ovary syndrome are much more likely than controls to have sleep disordered breathing (SDB) and daytime sleepiness.35

For further information see:
Polycystic Ovary Syndrome Symptoms
Verity - The Polycystic Ovaries Syndrome Self Help Group

Reactive Hypoglycemia
The term reactive hypoglycemia commonly describes a condition in which blood sugars fall below normal 2-4 hours after a high carbohydrate meal. It is thought to represent a consequence of excessive insulin release triggered by a carbohydrate meal.  Reactive Hypoglycemia is often a pre-curser to diabetes.

The prevalence of this condition is difficult to ascertain and controversial, because a number of stricter or looser definitions have been used, making it unclear as to the true criteria for reactive hypoglycemia.

Common Symptoms: fatigue, headaches, palpitations, depression nervousnes, irritability, tremors, flushing, cravings for sweets, increased appetite, rhinitis, sweating,

Some health professionals recommend a diet high in protein and low in carbohydrates. 

Other suggestions include:
eat small meals and snacks about every 3 hours
exercise regularly
choose high-fiber foods
avoid or limit foods high in sugar, especially on an empty stomach

Reactive hypoglycemia is often present in those who have fibromyalgia.  For more information about reactive hypoglycemia and fibromyalgia see Fibromyalgia And
Information from Dr. Starlanyl on Reactive Hypoglycemia and Fibromyalgia

Some information suggests that Reactive Hypoglycemia may be caused by food intolerance

Also see: Hypoglycemia

Sleep Apnea
Sleep apnea is a condition in which a person stops breathing for seconds and sometimes over a minute, several to many hundreds of time during the night, often without their knowledge. This condition is serious if left untreated because it can cause death.

Many studies indicate that sleep apnea and insulin resistance are closely related.  Studies show that Obstructive Sleep Apnea (OSA) is an independent risk factor for insulin resistance. 36, 37.38  One study showed that insulin levels are elevated in sleep apnea independent of obesity.35   Insulin resistance is reduced after only 2 days of treatment for sleep apnea.35,38 

Women with polycystic ovary syndrome (PCOS), a condition associated with insulin resistance, are more likely to have sleep disordered breathing (SDB) and daytime sleepiness which suggests a pathogenetic role of insulin resistance in Sleep apnea.35

Sleep disorders
Sleeping too little or too much increases a persons chance of getting diabetes.17

Decrease Your Sleep and Increase Your Risk for Diabetes

Insomnia, sleep apnea and night eating syndrome all appear to affect blood sugar control in a negative way and may make diabetes more likely. 


Vitamin D
Vitamin D Supplementation is preventative for type 1 diabetes.  Low levels are associated with insulin resistance and supplementation is useful for those with type 2 diabetes who are low in vitamin D.

Vitamin E
Low blood levels in diabetes

People who have low blood levels of Vitamin E are more likely to develop type 2 diabetes.5 Double blind studies show that Vitamin E improves glucose tolerance in people with type 2 diabetes.6,7 Vitamin E prevents blood from clotting too fast and has other effects that protect diabetics' blood vessels from damage.  It also protects animals from diabetic cataracts.

It may require 3 or more months of supplementation for benefits to become apparent.  The most common amount used is 900IU per day.8

Zinc
Increased urinary loss in diabetics

Zinc is a mineral that is involved in virtually all aspects of insulin metabolism.  Increased urinary loss of zinc is a commonly encountered feature of diabetes.3

Supplementation has been shown to improve insulin levels in both type I and type II diabetes.4

 

NOTE: Before taking any supplements, consult with your health care provider. The information presented here is not intended to diagnose, treat, cure or prevent any disease. We do not accept any responsibility for the use or misuse of any of the information contained herein.

Animal Testing Note: Web Shop Emporium occasionally lists references to studies that have been conducted on animals. We do not condone testing on animals but we feel it is a useless waste of their lives to ignore the health information that has been obtained in the past.   We subscribe to the position of many, including The Physician's Committee for Responsible Medicine, that there are other, more effective means of ensuring the safety and efficacy of medications and other products

In an effort to help end animal testing, we only list cosmetics and supplements that have been produced by companies that do not use animal testing for their ingredients or products unless it is required by law.

For further information please see:
Animal testing.  The basics and how to avoid buying products that are tested on animals.
 

References
1.Facchini F, Coulston AM, Reaven GM, Relation between dietary vitamin intake and resistance to insulin-mediated glucose disposal in healthy volunteers. Am J Clin Nutr. 1996 Jun;63(6):946-9
Entrez PubMed Abstract

2. Perdichizzi G, Bottari M, Pallio S, Fera MT, Carbone M, Barresi G., "Gastric infection by Helicobacter pylori and antral gastritis in hyperglycemic obese and in diabetic subjects", New Microbiol. 1996 Apr;19(2):149-54.
Entrez PubMed Abstract

3.  Tuvemo T, Gebre-Medhin M., "The role of trace elements in juvenile diabetes mellitus.", Pediatrician. 1983-85;12(4):213-9.
Entrez PubMed

4.  S.M. Hegazi et al, "Effect of zinc Supplementation on Serum Glucose, Insulin, Glucagon, Clucose-6-Phosphatase, and Mineral Levels in Diabetics,," J. Clin. Biochem Nutr 12 (1992): 209-15

5.  Salonen JT, Nyssonen K, Tuomaninen T-P, et al, "IIncreased risk of non-insulin dependent diabetes mellitus at low plasma vitamin E concentrations: a four year follow up study in men.", BMJ. 1995 Oct 28;311(7013):1124-7.
Entrez PubMed

6. Paolisso G, D'Amore A, Giugliano D, Ceriello A, Varricchio M, D'Onofrio F., "Pharmacologic doses of vitamin E improve insulin action in healthy subjects and non-insulin-dependent diabetic patients.", Am J Clin Nutr. 1993 May;57(5):650-6.
Entrez PubMed

7. Paolisso G, D'Amore A, Galzerano D, Balbi V, Giugliano D, Varricchio M, D'Onofrio F.,  "Daily vitamin E supplements improve metabolic control but not insulin secretion in elderly type II diabetic patients." Diabetes Care. 1993 Nov;16(11):1433-7.
Entrez PubMed

8.  Skye Lininger, D.C., Editor in Chief, Jonathan Wright, M.D., Steve Austin, N.D., Donald Brown, N.D. and Alan Gaby, M.D. "The Natural Pharmacy"

9.  Phyllis A. Balch, CNC, "Prescription for Nutritional Healing, A practical A-To-Z Reference to Drug-Free Remedies Using Vitamins Minerals, Herbs and Food Supplements"

10. Robert C. Atkins,  "Dr. Atkins' Vita-Nutrient Solution : Nature's Answer to Drugs"

11.  Schulze MB, Hu FB., "PRIMARY PREVENTION OF DIABETES: What Can Be Done and How Much Can Be Prevented?", Annu Rev Public Health. 2005 Apr 21;26:445-467.
Entrez PubMed

12.  Takaya J, Higashino H, Kobayashi Y., "Intracellular magnesium and insulin resistance.", Magnes Res. 2004 Jun;17(2):126-36.
Entrez PubMed

13.  J.R. White and R.K. Campbell, "Magnesium and Diabetes: A Review", Ann Pharmacother 27 (1993), 775-80
Entrez PubMed

14.  Acbay O, Celik AF, Kadioglu P, Goksel S, Gundogdu S., "Helicobacter pylori-induced gastritis may contribute to occurrence of postprandial symptomatic hypoglycemia.", Dig Dis Sci. 1999 Sep;44(9):1837-42.
Entrez PubMed

15.  Peach HG, Barnett NE., "Helicobacter pylori infection and fasting plasma glucose concentration", J Clin Pathol. 2001 Jun;54(6):466-9.
Entrez PubMed

16.  Qin LQ, Li J, Wang Y, Wang J, Xu JY, Kaneko T, "The effects of nocturnal life on endocrine circadian patterns in healthy adults", Life Sci. 2003 Sep 26;73(19):2467-75.
Entrez PubMed.

17.  Ayas NT, White DP, Al-Delaimy WK, Manson JE, Stampfer MJ, Speizer FE, Patel S, Hu FB., "A prospective study of self-reported sleep duration and incident diabetes in women", .Diabetes Care. 2003 Feb;26(2):380-4.
Entrez PubMed

18.  Paskaloglu K, Sener G, Ayangolu-Dulger G., "Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum.", Eur J Pharmacol. 2004 Sep 24;499(3):345-54.
Entrez PubMed

19.  Fabis M, Pruszynska E, Mackowiak P., "In vivo and in situ action of melatonin on insulin secretion and some metabolic implications in the rat.", Pancreas. 2002 Aug;25(2):166-9.
Entrez PubMed

20.  Nishida S, Segawa T, Murai I, Nakagawa S., "Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity.", J Pineal Res. 2002 Jan;32(1):26-33.
Entrez PubMed

21. Tishler M, Smorodin T, Vazina-Amit M, Ramot Y, Koffler M, Fishel B., "Fibromyalgia in diabetes mellitus.", Rheumatol Int. 2003 Jul;23(4):171-3. Epub 2003 May 20.
Entrez PubMed

22.  Patucchi E, Fatati G, Puxeddu A, Coaccioli S., [Prevalence of fibromyalgia in diabetes mellitus and obesity], Recenti Prog Med. 2003 Apr;94(4):163-5..
Entrez PubMed

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