Salicylate free Supplements
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Reactive
Hypoglycemia may be caused by food intolerance, including salicylates in
food
Salicylates in Foods - Teas are relatively high in salicylates
Aspirin sensitivity and urticaria
Symptomatic patients with celiac disease who are on gluten free diet
sometimes have a salicylate intolerance
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Salicylate Intolerance Links and information
Some individuals feel that they have a salicylate
intolerance or allergy that causes them serious health problems. Some have reported a wide range of symptoms that they feel are alleviated by strict avoidance of salicylates
in food and other products.
WebMD
states that salicylate sensitivity symptoms vary but may include a
life-threatening reaction involving a severe drop in blood pressure, loss of
consciousness, and organ system failure. Other possible symptoms are:
- Asthma-like symptoms, such as trouble breathing and
wheezing
- Headaches
- Nasal congestion
- Changes in skin color
- Itching, skin rash or hives
- Swelling of the hands, feet, and face
- Stomach pain
According to the FDA, 5% of the population is
sensitive to salicylates. Symptoms such as itching, broncho-spasm and
localized swelling that can be life-threatening can occur, even in those
with no prior history of sensitivity to salicylates.
US FDA/CFSAN
It is well known and accepted that
Reyes
Syndrome is connected to ingestion of medications with salicylates and that
many with asthma are highly sensitive and often unable to tolerate
medications with salicylates. However there has
been little if any exploration of salicylate allergy or intolerance, even in those with
known health problems that have a connection to salicylates such as Reyes
syndrome and asthma.
There are those, including some in the medical community that feel that ADHD
and ADD may be related to ingestion of salicylates. To further explore
that relationship, please see the
Feingold Association homepage
Of particular interest to those with Fibromyalgia, Chronic Fatigue
Syndrome and similar illnesses is that
most of the symptoms that are mentioned for salicylate intolerance are symptoms that are associated with
Fibromyalgia Syndrome (FMS) and Chronic Fatigue And Immune Dysfunction
Syndrome (CFIDS). It seems possible that some who have been diagnosed with
FMS or CFIDS may have a problem with salilcylates.
Interestingly enough, many with FMS and CFIDS have had improvement in their
condition by following the
guaifenesin protocol, part of which requires that
one avoid topical and concentrated salicylates but not salicylates in food. In the guaifenesin
protocol, the avoidance of salicylates is required because salicylates block
the medication (guaifenesin) from working properly, not because of a perceived problem with
a salicylate intolerance. It does seem possible that there are a
subset of individuals who show improvement because they are avoiding salicylates. These
individuals may show even more improvement if they were to change their
diet to avoid salicylates. For more information see:
Your complete guide to Salicylate sensitivity
Salicylates and Blood Sugar
Salicylate is listed as a drug that may be related to hypoglycemia.
eMedicine -
Hypoglycemia : Article by Frank Smeeks, MD, FAAEM
Aspirin is a salicylate. Doses of salicylates that
are commonly used to treat rheumatoid arthritis (4-6 grams per day) may
induce hypoglycemia in both non-diabetic and diabetic adults and may reduce
insulin requirements in type 1 diabetes. 3
People with impaired kidney function should be careful in their use of
salicylates. A case of hypoglycemia was reported in the Archives of
Internal Medicine to be caused by topical salicylate use in an elderly man
with reduced kidney function.4
A salicylate free diet is recommended by these allergy specialists for
people who are having difficulty getting rid of hypoglycemia.
Reactive Hypoglycemia
may be caused by food intolerance, including salicylates in food
According to this research, salicylate might be considered in the therapy of
type 2 diabetes someday.
Prevention of fat-induced insulin resistance by salicylate
Salicylates and Contact Dermatitis
One study of 6 patients with contact dermatitis
of the lips determined that 5 of the 6 patients were allergic to phenyl
salicylate.1 It was noted at St. Luke's Hospital in the
United Kingdom that a 2 year old had urticaria that did not respond to
antihistamine therapy. It was found that she was using a topical salicylate
preparation that was regularly being applied to her pacifier. Her urticaria
cleared and has not recurred once they stopped the topical.2
There are many other accounts of these types of reactions to topical
salicylates.
Salicylates and Bacteria
Salicylates are used by plants to fend off bacteria,
viruses and other pests. Salicylates do have an affect on bacteria and
in fact, cause some bacteria to become resistant to certain antibiotics.
The effects of salicylate on bacteria
Salicylate
induction of phenotypic resistance to quinolones in Serratia marcescens --
Berlanga and Viñas 46 (2): 279 -- Journal of Antimicrobial Chemotherapy
Salicylate Reduces
Susceptibility of Mycobacterium tuberculosis to Multiple Antituberculosis
Drugs -- Schaller et al. 46 (8): 2636 -- Antimicrobial Agents and
Chemotherapy
Hopefully, more studies will be forthcoming that will help determine the
extent of salicylate intolerance and it's affect on health. Following
are links that may help you to further explore this subject.
Salicylate intolerance in diseases of the
lower gastrointestinal tract
Patients with chronic active disease who have inflammatory bowel disease and
food allergies should be evaluated for salicylate intolerance.5
Links
Entrez PubMed "Salicylate sensitivity in Children reported to respond
to salicylate exclusion"
Symptoms of Additive/Salicylate Sensitivity
Your complete
guide to Salicylate sensitivity
WebMD Salicylate
Allergy
National Reye's Syndrome Foundation Home Page
eMedicine - Toxicity, Salicylate : Article by Lance W Kreplick, MD, MMM
Salicylates, Amines and Glutamate booklet introduction - RPAH Allergy Unit
Salicylate (Aspirin) Ingestion/California Poison Control
"Salicylates directly or indirectly affect most
organ systems in the body by uncoupling oxidative phosphorylation,
inhibiting Krebs cycle enzymes, and inhibiting amino acid synthesis."
Sal-FreeTM Centre - Various Data Bases & Information regarding salicylates
Lots of useful information about salicylates as it applies to the
guaifenesin protocol
Plant Choices -
Phytochemeco Databases
ADHD Diet - Feingold Association - Feingold diet for ADHD
Salicylate
Free Diet
Diets for Special Problems - Hives and salicylates
Salicylate List for foods
Food
Salicylate Content List
Salicylates in
Food - Swain Study
References
1. Calnan CD, Cronin E, Rycroft RJ., "Allergy
to phenyl salicylate.", Contact Dermatitis. 1981 Jul;7(4):208-11.
Entrez PubMed
2. Wright AL, Minford A., "Urticaria and hidden salicylates.", Pediatr
Dermatol. 1999 Nov-Dec;16(6):463-
Entrez PubMed
3. Manjula K. Pandit; John Burke; Anthony B. Gustafson; Anil Minocha; and
Alan N. Peiris, "Drug-induced Disorders of Glucose Tolerance", annals of
internal medicine:1 April 1993 | Volume 118 Issue 7 | Pages 529-539
Drug-induced
Disorders of Glucose Tolerance -- Pandit et al. 118 (7): 529 -- Annals of
Internal Medicine
4. R. Raschke, P. A. Arnold-Capell, R. Richeson and S. C. Curry,
"Refractory hypoglycemia secondary to topical salicylate intoxication",
Archives of Internal medicine Vol. 151 No. 3, March 1, 1991
Arch
Intern Med -- Abstract: Refractory hypoglycemia secondary to topical
salicylate intoxication, March 1, 1991, Raschke et al. 151 (3): 591
5. Raithel M, Baenkler HW, Naegel A, Buchwald F, Schultis HW,
Backhaus B, Kimpel S, Koch H, Mach K, Hahn EG, Konturek PC., "Significance
of salicylate intolerance in diseases of the lower gastrointestinal tract.",
J Physiol Pharmacol. 2005 Sep;56 Suppl 5:89-102.
Significance of salicylate intolerance in diseases of the lower
gastrointestinal tract.
The information presented here is not intended to
diagnose, treat, cure or prevent any disease. We do not accept any
responsibility for the use or misuse of any of the information contained
herein.
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